(1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)Chemicalbookbutanoyl){{10}},6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylicacid CAS 2755812-45-2

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ProductName:(1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)Chemicalbookbutanoyl){{10}},6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylicacid CAS 2755812-45-2

 

{{0}}Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-[(2S)-3,3-dimethyl-1-oxo-2-[(2,2,2-trifluoroacetyl)amino]butyl]-6,6-dimethyl-, (1R,2S,5S)-;

 

Assay: 99%+

Boiling point:495.1±45.0 degree

Pka:3.26±0.40

Density:1.290±0.06 g/cm³

 

It is intermediate of Paxlovid. PF-07321332 (nirmatrelvir) is an oral antiviral clinical lead. It is a covalent inhibitor of SARS-CoV-2 Mpro (main protease, 3CLpro) that binds to cysteine145 within the enzyme's catalytic domain. Mpro is essential for coronavirus replication. Inhibiting Mpro actvity blocks replication at an early stage in the virus' life cycle. Due to structural similarities between the Mpro's of other coronavirusus, PF-07321332 offers the potential of pan-coronavirus activity. In vitro it is suggested to inhibit replication of CoV-2 variants including delta and omicron.

 

 

maq per Qat: (1r,2s,5s)-3-((s)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)chemicalbookbutanoyl){{10}},6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylicacid cas 2755812-45-2, manufacturers, suppliers, factory, buy, in stock

• chopmeH: Cholic Acid CAS 81-25-4
• veb: (1R,2S,5S)-N-((S)-1-amínó-1-oxó-3-((S)-2-oxópýrrólidín-3-ýl)própan{ {10}}ýl)-3-((S)-3,3-dímetýl-2-(2,2,2-tríflúorasetamídó)bútanóýl )-6,6-dímetýl-3-asabísýkló[3.1.0]hexan-2-karboxamíð CAS 2755812-81-6